EndoWize A Modern Endodontic Irrigator

EndoWize is lethal to 99.9999% of bacteria yet harmless to your patients

What is EndoWize?

EndoWize is a new endodontic irrigant that gives dental practitioners the confidence in performing root-canal procedures: it helps lubricate instruments, flushes debris, reduces smear layer and kills bacteria. 

 EndoWize endodontic irrigator also contains a gentle biocide (Hypochlorous or HOCl), that is produced by human white blood cells to phagocytose and destroy pathogens after the skin has been damaged (eg cuts, burns etc). 

Tests on the effect of HOCl on soft tissue,wounds, skin and the eye show
it to be non-irritating and non-sensitising (1). These unique properties have resulted in the use of HOCl in a wide variety of applications, including burns management, leg ulcers, food hygiene, water treatment and clinical disinfection, with independent testing proving the elimination of 99.9999% of pathogens, both in Vivo and in vitro.

 Over 460 different types of bacteria have been identified as commonly present in infected root canals root canals (2). EndoWize is active against all of these pathogens including e.faecalis which is commonly found in re-treatment cases (3). HOCl (also known as oxidative potential (OP) or Acid electrolytic (AE) water) has been proposed as an endodontic irrigant for over 20 years (4)

Naturally occurring HOCl is extremely unstable and will rapidly turn into
a saline solution (24 hours).  EndoWize’s unique manufacturing
process produces HOCl in an enhanced, stable form (1 year shelf life) that is suitable for specific clinical applications.

Endo-wise is lethal to bacteria
EndoWize is effective against 99.9999% of bacteria including e.faecalis as shown here.

Over 460 different types of bacteria have been identified as commonly present in infected root canals. EndoWize is active against all of these
pathogens including e.faecalis which is commonly found in re-treatment cases.

References:
1
Diversity of endodontic microbiota revisited
Siqueira JFJ., Rocas IN... J Dent Res 
2009 88:969-81
2
Isolation of Enterococcus faecalis in previously root-filled canals in a Lithuanian population.
V, Balciuniene I, Eriksen HM, Haapasalo M.  J Endod. 
2000 26:593–595
3
Hypochlorous acid as a potential wound care agent: part I. Stabilized hypochlorous acid: a component of the inorganic armamentarium of innate immunity.
Wang L,Bassiri M, Najafi R, Najafi K, Yang J, Khosrovi B, Hwong W, Barati E, Belisle B, Celeri C, Robson MC. J Burns Wounds.
2007 Apr 11;6:e5
4
Removal of smear layer in the root canal using oxidative potential water.
Hata G, Uemura M, Weine FS, Toda T. J Endod.
1996 Dec;22(12):643-5

EndoWize - The Safer Way

There are several commonly used endodontic irrigants. They have varying degrees of antibacterial activity. A recent Cochrane report and subsequent BDA review advised that there is;

“Insufficient reliable evidence showing superiority of one irrigant over another” (5)

All of the other common irrigants contain harsh chemicals which pose inherent risks
to operators and patients. (6,7). These include Sodium Hypochlorite, Chlorhexidine, EDTA and Hydrogen peroxide. By contrast, EndoWize is lethal to 99.9999% of bacteria yet harmless to your patients, when used correctly.

5
Irrigants for non-surgical root canal treatment in mature permanent teeth. Cochrane Database Syst Rev. 2012 Sep 12;(9)
Fedorowicz Z1, Nasser M, Sequeira-Byron P, de Souza RF, Carter B
2012 Sep 12
6
BDA evidence report https://www.bda.org/dentists/education/sgh/Documents/Irrigation%20in%20endodontics%202.pdf
N/A
N/A
7
Complications during root canal irrigation—literature review and case reports
Hülsmann M, Hahn W.. Int Endod J
2000;33:186-93
8
. Long-term paresthesia following inadvertent forcing of sodium hypochlorite through perforation in maxillary incisor. Endod Dent Traumato
Reeh ES, Messer HH.
1989;5:200-3

Technical Information & Usage

Using Endo-wise

EndoWize is compatible with endodontic materials, instruments and techniques. You don’t need to do anything different - to be safer

Endo-wise Modern Endodontic Irrigator

Using EndoWize

No need to change your technique
Use standard irrigating syringes and irrigating needles
Compatible with hand and rotary files
Compatible with root canal filling materials
Compatible with ultrasonic, endosonic or positive pressure irrigating devices

Clinical Technique

1.    Isolate the tooth in the normal manner, ideally with a rubber dam.
2.    Access pulp chamber in normal manner.
3.    EndoWize can be used with any endodontic syringe,
4.    Copious irrigation of pulp chamber will aid the location of canals.
5     Shape canals with your usual technique -EndoWize is most effective if the canal is irrigated after every instrument.
6.    To further enhance EndoWize, once the canal is shaped, rinse with EDTA for 30 seconds followed by a final flush with          EndoWize for 30 seconds.
7     Fill the canal with our preferred inter-visit dressing or permanent obturation method.

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